Vitiligo is a chronic skin condition that causes areas of the skin to become depigmented (or lose pigment). Considered an autoimmune disease, vitiligo is thought to occur when the body’s immune system attacks and destroys melanocytes (the cells that produce pigment) — leaving the affected area of skin void of color. Vitiligo most often affects the face, elbows, knees, hands and feet, and the condition is more noticeable in people with darker skin tones.